Justin M. Gregory, MD, MSCI

Justin M. Gregory, MD, MSCI

Assistant Professor of Pediatrics
Department of Pediatrics
Delivery Address
Village at Vanderbilt
1500 21st Ave S
Room / Suite
Suite 1514
Nashville
Tennessee
37212-8285
Phone
(615) 322-7427

Specialty
Endocrinology, Pediatric
M.D.
University of Tennessee Health Sciences, Memphis, TN, 2008
Residency
Pediatric Residency-University of Tennessee, LeBonheur Children's Medical Center, Memphis, TN
Fellowship
Pediatric Endocrinology Fellowship-Vanderbilt University Medical Center, Nashville, TN

Clinical Interests

Type 1 diabetes;  glucose metabolism;  iatrogenic hyperinsulinemia;  insulin resistance;  endothelial dysfunction

Research Information

Dr. Gregory's type 1 diabetes research seeks to mechanistically define the deleterious metabolic and cardiovascular effects of iatrogenic hyperinsulinemia caused by peripheral insulin delivery. He is working to translate these findings into therapeutic strategies that will restore an appropriate balance of insulin between the liver and insulin-sensitive peripheral tissues, such as hepatopreferential and oral insulin analogs and intraperitoneal insulin delivery. Ultimately, he aims to quantify the cardiovascular benefits gained when the appropriate insulin balance between hepatic and peripheral tissues is restored. Dr. Gregory's research utilizes the conscious, catheterized canine model to manipulate metabolic and hormonal conditions in vivo. He also conducts cardiometabolic research in humans in the Clinical Research Center at Vanderbilt.

 

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