James D. Chappell, MD, PhD
Vanderbilt University, 1997
Vanderbilt University School of Medicine, 2001
Pathology Residency-Vanderbilt University School of Medicine Department of Pathology
Post-doctoral Fellowship-Vanderbilt University School of Medicine Department of Pediatrics
Microbiology Fellowship-Vanderbilt University School of Medicine Department of Pathology
Viral diseases, Vaccines, Antivirals, Viral replication
Dr. Chappell's scientific interests encompass the biology, pathogenesis, etiology, and prevention of viral diseases, emphasizing infections of the respiratory and enteric systems. He has investigated structural and functional principles governing virus cell-targeting and replication programs using model systems of virus-cell interactions and more recently focused on replication mechanisms and countermeasures development against highly virulent emerging viruses, specifically, Middle East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS) coronaviruses. Other ongoing collaborative research includes the contemporary pathogen spectrum and genetic diversity, clinical features, and vaccine-mediated prevention of acute viral respiratory and gastrointestinal infections of children.