Dr. Patrick's work focuses on identifying and characterizing pathogenic molecular pathways in juvenile idiopathic arthritis and pediatric autoimmune disease.  Her research program employs the study of rare monogenetic mutations associated with disease manifestations to discover novel pathways involved in autoimmunity.  This strategy defines the relationship of these pathways to the broader disease population.  She has elucidated the role of GATA3, a gene critical for T cell differentiation and function, in juvenile idiopathic arthritis.  Her research program involves studies in primary human cells using molecular biology, immunology, and next generation sequencing techniques. 

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