Samantha J. Eagle, DNP, APRN, CPNP-AC

Samantha
J.
Eagle
DNP, APRN, CPNP-AC
Nurse Practitioner
Allergy/Immunology/Pulmonary Medicine
Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
11215
Nashville
Tennessee
37232-9500
s.eagle@vumc.org

Pediatric palliative care, Asthma

Mariana Bedoya, MD

Mariana
Bedoya
MD
Assistant Professor of Pediatrics
Allergy/Immunology/Pulmonary Medicine
Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
11215
Nashville
Tennessee
37232-9500
mariana.bedoya@vumc.org

Pediatric Pulmonary Medicine, Pediatric Sleep Medicine

M.D.
Universidad de San Martin de Porres, Lima, Peru, 2010
Residency
Pediatrics - University of Miami/Jackson Memorial Hospital, Miami, FL, 2016
Fellowship
Pediatric Pulmonary Fellowship - University of Miami/Jackson Memorial Hospital, Miami, FL, 2019
Sleep Medicine Fellowship - Cincinnati Children's Hospital, Cincinnati, OH, 2020

Jason R. Schwartz, MD, PhD

Jason
R.
Schwartz
MD, PhD
Assistant Professor of Pediatrics
Hematology/Oncology
(615) 936-1762
Delivery Address
Preston Research Building
2220 Pierce Avenue
Room / Suite
397
Nashville
Tennessee
37232-6311

Dr. Schwartz’s research studies seek to understand the molecular mechanisms and pathogenesis underlying pediatric myelodysplastic syndromes (MDS), specifically those syndromes caused by germline mutations in SAMD9 and SAMD9L.

His current focus is to better understand the biological consequences of SAMD9 and SAMD9L mutations in MDS through genomic and functional investigations in an induced pluripotent stem cell (iPSC) model system of pediatric MDS. This iPSC model system was developed through CRISPR/Cas9 knock-in of known pathogenic SAMD9 or SAMD9L mutations at the respective endogenous locus. Using additional CRISPR tools, Dr. Schwartz is working to selectively activate or repress transcription of these loci and interrogate differential expression patterns that result using RNA sequencing. These studies will help to uncover the important cellular functions of these two interesting genes.

Additionally, Dr. Schwartz hopes to describe the mechanisms and clonal evolution that underlie the SAMD9/9L-mediated development of monosomy 7 and, in some patients, subsequent spontaneous hematopoietic recovery through single-cell multi-omics. The knowledge gained from a deeper understanding of how SAMD9/9L mutations and chromosome 7 loss effects hematopoiesis and how these lesions clonally evolve over time will lead to the ability to deeply surveil patients with predispositions to develop MDS/AML. Thus, resulting in the ability to predict which patients may not need bone marrow transplant (particularly some of those patients with germline SAMD9/9L mutations), but also identify which patients are at highest risk of AML development such that transplant can occur prior to the development of malignancy.

Dr. Schwartz’s research and early physician-scientist career are supported through grant funding through the National Heart, Lung, and Blood Institute and Alex’s Lemonade Stand Foundation. He was also appointed as a Carolyn Perot Rathjen Faculty Fellow. Dr. Schwartz’s clinical interests are also focused on pediatric inherited and acquired bone marrow failure and utilizing clinical genomic sequencings to guide therapy decisions.

>> View Publications on PubMed

jason.schwartz@vumc.org

SAMD9/9L-related syndromes, Inherited bone marrow failure syndromes, Pediatric myelodysplastic syndrome, Pediatric therapy-related myeloid neoplasms

Specialty
Hematology/Oncology, Pediatric
M.D./Ph.D.
LSU Health Sciences Center – New Orleans, New Orleans, LA, 2004-2011
Residency
Pediatrics - Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, 2011-2014
Fellowship
Pediatric Hematology/Oncology - St. Jude Children's Research Hospital (SJCRH), Memphis, TN, 2014-2017
Physician-Scientist Training Program
St. Jude Children's Research Hospital (SJCRH), 2017-2018, Mentor: Jeffery Klco, MD, PhD

Laleh Bahrami, MD

Laleh
Bahrami
MD
Assistant Professor of Pediatrics
General Pediatrics
Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
8232
Nashville
Tennessee
37232-9226
laleh.bahrami@vumc.org

Autism spectrum disorder, health equity, medical education

Specialty
General Pediatrics
M.D.
Tulane University School of Medicine, 2014
Residency
Children's Hospital of Philadelphia, 2014-2016
UCLA, 2016-2017

Emma G. Carter, MD

Emma
G.
Carter
MD
Assistant Professor of Pediatrics
Pediatric Neurology

Dr. Emma Carter is a pediatric neurologist and epileptologist at Vanderbilt University Medical Center. Her clinical interests include Pediatric epilepsy, fetal and neonatal neurology, genetic diseases of the nervous system, cerebral palsy, and palliative medicine. Dr. Carter obtained her medical degree and completed a residency in Pediatric Neurology at the Medical University of South Carolina in Charleston, South Carolina. She then went on complete a fellowship in Pediatric Epilepsy at Vanderbilt University Medical Center. She is board certified in both Neurology with Special Qualification in Child Neurology and Epilepsy. During her residency and fellowship, she was awarded for her passion in teaching and dedication to patient care, and she continues to have special interests in complex epilepsy care and medical education teaching medical students, residents, and fellows.

Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
9th Floor
Nashville
Tennessee
37232
emma.g.carter@vumc.org

Pediatric Epilepsy, Fetal and Neonatal Neurology, Genetic Diseases of the Nervous System, Palliative Medicine, Cerebral Palsy

Specialty
Child Neurology, Epilepsy
M.D.
Medical University of South Carolina, Charleston, SC, 2012
Residency
Child Neurology - Medical University of South Carolina, Charleston, SC, 2017
Fellowship
Pediatric Epilepsy - Vanderbilt University Medical Center, Nashville, TN, 2018

Sarah B. Hesney, CPNP

Sarah
B.
Hesney
CPNP
Nurse Practitioner
Developmental Medicine
Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
11101
Nashville
Tennessee
37232-9003
sarah.hesney@vumc.org

Autism, Developmental delays, ADHD

Caitlin Stone, PhD

Caitlin
Stone
PhD
Assistant in Pediatrics
Developmental Medicine
Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
11101
Nashville
Tennessee
37232-9003

Dr. Stone is interested in diagnostic evaluations for children, adolescents, and adults with concerns related to autism spectrum disorder, learning disorders, and developmental delays.

caitlin.stone@vumc.org

B.A.
Psychology and Child Development
M.A.
Clinical Psychology
Ph.D.
Clinical Psychology, University of North Carolina at Greensboro, Greensboro, NC
Pre-doctoral Internship
University of Rochester Medical Center, Rochester, NY

Kelly C. Bellm, APRN, CPNP

Kelly
C.
Bellm
APRN, CPNP
Nurse Practitioner
Hematology/Oncology
Delivery Address
Preston Research Building
2200 Children's Way
Room / Suite
397
Nashville
Tennessee
37232-6311
kelly.c.bellm@vumc.org

Pediatric Hemostasis and Thrombosis

Kirk M. Kerensky, MD

Kirk
M.
Kerensky
MD
Assistant Professor of Clinical Pediatrics
Outreach Medicine
(615) 936-9840
Delivery Address
2141 Blakemore Ave
Nashville
Tennessee
37212-3505
kirk.kerensky@vumc.org

Childhood obesity, Patient compliance

M.D.
University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA - 1978
Residency
Pediatrics - Children's Hospital of Pittsburgh, Pittsburgh, PA - 1981
Fellowship
Endocrinology, Metabolism & Diabetes Mellitus - Children's Hospital of Pittsburgh, Pittsburgh, PA - 1983

Madison Hatfield, APRN, CPNP, RN

Madison
Hatfield
APRN, CPNP, RN
Nurse Practitioner
General Pediatrics
Delivery Address
Doctors' Office Tower
2200 Children's Way
Room / Suite
8232
Nashville
Tennessee
37232-9226
madison.e.hatfield.1@vumc.org