Responsibilities on the clinical service include the evaluation and management of children admitted to Monroe Carell Jr. Children's Hospital at Vanderbilt, as well as outpatient consultations in the Pediatric Infectious Diseases Clinic, the Pediatric HIV clinic, and the Pediatric Emergency Department.

Inpatient care is divided into two services. The Edwards Service is responsible for the care of general infectious diseases while the Wright Service (Immunocompromised Host Service) cares specifically for children with underlying immunocompromising conditions, and fellows spend time on each service. Fellows will spend a total of 13 months in clinical training, distributed across the three years of training. All clinical activities are directly supervised by one-on-one interactions with faculty. Fellows also play an integral role in Pediatric Resident teaching conferences, Grand Rounds, and Infectious Diseases conferences, including a weekly pediatric ID conference moderated by the fellow on service. Fellows also have training experience in the Clinical Microbiology Laboratory and rotate with the Antimicrobial Stewardship Program during their first year.