Dr. Walsh's clinical research focuses on determining the optimal ways to care for critically ill infants. Recent projects include a randomized trial of nitric oxide for prevention of chronic lung disease in premature infants and a randomized trial of fetal surgery vs. post-natal repair of myelomeningocele. He is presently looking at the effects of state-wide screening for critical congenital heart disease on outcomes. He is also studying the use of erythropoietin to ameliorate injury from hypoxic ischemic encephalopathy and working with colleagues in nursing to research pregnancy outcomes in Tennessee and the effect of targeted interventions.