Dr. Choi investigates the role of redox-based signaling in blood vessel inflammation. Her focus is on the pro-inflammatory cytokine, tumor necrosis factor alpha (TNFα) and the impact of receptor endocytosis on its signaling in the vasculature. Specifically, she is interested in how TNFα receptor endocytosis impacts the balance of signaling processes that occur at the cell surface vs. within receptor containing “signaling” endosomes.

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