Mandy was raised in Lincoln, Nebraska. She attended Creighton University for college in Omaha, Nebraska where she studied biology. She then spent a gap year working with the Jesuit Volunteer Corps in Detroit, Michigan where she worked as a resource navigator at a clinic. She attended the University of Nebraska for medical school where she developed passions for health equity work, medical education, and basic science and clinical research.

Outside of medicine, Mandy enjoys spending time with her family and herd of goldendoodles, playing with her amazing nephews, chefing it up in the kitchen, volleyball, and watching a good movie.