Nathan Bingham, MD, PhD

Nathan Bingham, MD, PhD

Assistant Professor of Pediatrics
Pediatric Endocrinology and Diabetes
Office Address
Village at Vanderbilt
1500 21st Ave S
Room / Suite
Ste 1514
Nashville
Tennessee
37212-8285
Phone
(615) 322-7427

Specialty
Endocrinology, Pediatric
Ph.D.
University of Texas Southwestern Graduate School of Biomedical Sciences, Dallas, TX, 2007
M.D.
University of Texas Southwestern Medical School, Dallas, TX, 2008
Residency
Pediatric Residency-Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Fellowship
Pediatric Endocrinology Fellowship-Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Clinical Interests

Prader-Willi Syndrome, Type 1 Diabetes, Type 2 Diabetes, Thyroid disorders, Adrenal disorders, Puberty disorders, short stature

Research Information

Diets rich in fat content have been shown to induce a state of chronic, low-grade inflammation within the hypothalamus, a brain region critical in the regulation of appetite and body weight. This inflammation has been shown to disrupt the normal functions of the hypothalamus, altering the hormonal and neuronal signals that regulate energy balance and contributing to continued weight gain. The Bingham lab uses mouse models of obesity to evaluate the mechanisms leading to the development of high-fat diet-induced hypothalamic inflammation. In addition, we use mouse models of bariatric surgery to evaluate the effects that this common obesity treatment has on hypothalamic inflammation. We hope that these tools will lead to a better understanding of the cellular and molecular mechanisms that contribute to the development of hypothalamic inflammation and lead to novel treatments for obesity.

 

>> View Publications on PubMed