Mark R. Denison, MD

Mark R. Denison, MD

Professor of Pediatrics and Pathology, Microbiology and Immunology
Pediatric Infectious Diseases
Edward Claiborne Stahlman Chair in Pediatrics
Medical Center North
1161 21st Avenue South
Room / Suite
D-7219
Nashville
Tennessee
37232-2581

Specialty
Infectious Diseases, Pediatric
M.D.
University of Kansas, Kansas City, KS, 1980
Residency
Residency-University of Iowa Hospitals, Iowa City, IA
Fellowship
Fellowship-University of Iowa Hospitals, Iowa City, IA

Clinical Interests

Pediatric Infectious Diseases, Virology, Antivirals, Vaccines, Emerging Infections

Research Information

The Denison Lab studies the coronaviruses (CoVs), specifically Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). They work to define the mechanisms of virus evolution and adaptation. Ongoing projects include studies of a unique virus-encoded RNA proofreading enzyme in coronavirus evolution and disease, studies of potential therapeutic monoclonal antibodies, and testing of highly active antiviral nucleoside analogs against all CoVs. Dr. Denison has trained graduate students, postdocs, medical students, undergraduates and faculty in virology research. Dr. Denison directs a T32 (training grant) for ID Fellows and postdoctoral scientists, and is a training director for the Pediatrics K12 physician-scientist training grant.

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